Love To Run Border Collies
We have dedicated a page to describe and help provide an understanding on the diseases we can test for in border collies. There is no excuse to breed dogs with no health testing! Some of these diseases can be deadly, yet they are so easily preventable by health testing before breeding!
An important point to remember is an animal may result as a "carrier" for a certain disease. This does not mean they have the disease it means they carry the gene. If the carrier is mated to a "Clear" dog the puppies will not get the disease. Please refer to the chart below.
The diseases that can be found in border collies that we can test for include:
Is an abnormal formation of the hip socket. It will result in severe pain, muscle weakness and early arthritis.
Cobalamin Malabsorption: Cubilin Deficiency:
Is a condition where dogs are unable to effectively make adequate amounts of a type of protein that plays a role in the absorption of nutrients from the intestinal tract and kidneys. Symptoms include anorexia, lethargy, poor weight gain, poor muscle mass, severe neurological dysfunction, seizures, coma and death.
Collie Eye Anomaly/Choroidal Hypoplasia:
Collie Eye Anomaly is a defect in the eye’s formation.
Is a disease where the hind feet will start to knuckle over progressing to total paralysis. Once a dog shows these signs it will almost always respond poorly to therapy. Eventually it progresses from the middle of the spinal cord to the upper cord and brain stem, leading to forelimb weakness and eventually interference with the muscles of breathing, causing death.
Goniodysgenesis and Glaucoma
Glaucoma is a condition in which pressure is placed on the eye, causing inadequate fluid drainage in the eye. If the condition becomes chronic or persists without treatment, it will eventually cause permanent damage to the optic nerve, resulting in blindness.
Goniodysgenesis is an abnormality of the anterior chamber of the eye, and it has been associated with glaucoma and blindness.
Ivermectin Sensitivity MDR1 (Multi Drug Resistance):
Is a sensitivity to certain drugs. When given the selected drugs it can cause seizures.
Neuronal Ceroid Lipofuscinosis:
Ceroid Lipofuscinosis is an inherited disorder targeting the nervous system. Symptoms not showing until approximately 15 months of age. It is fatal.
Primary Lens Luxation:
Lens luxation refers to the lens being in an abnormal position inside the eye. It can cause blindness.
Raine Syndrome Dental Hypomineralisation:
The disorder causes severe tooth wear resulting in pulpitis and requiring extraction of those teeth. It causes significant wear of the teeth. Lower incisor teeth can be worn close to the gingival margin. The enamel shows a light brown discoloration and appears dull. Some worn teeth can have a pulp exposure and pulpIits as a result of the wear.
Trapped Neutrophil Syndrome:
It is an inherited condition that affects the immune system where the body produces white blood cells but cannot release them into the bloodstream. Usually dogs do not make it over 4 months old but have lasted up to 2 years before.
von Willebrand's Disease Type II (RESEARCH ONLY):
Is a blood clotting disorder.
Is a disease of the sensory nerves, clinical signs include loss of coordination, joint laxity, lack of awareness where the limbs are in space, and inability to perceive pain. Affected dogs often have self-mutilated limbs, which may be due to tingling or pain in their paws, another manifestation of the disorder. Since the disorder is progressive and the symptoms are severe, affected dogs are usually euthanized.
Adult Onset Deafness:
Is the early onset of deafness.
Information provided has been collected and quoted by Orivet Genetic Pet Care. Please head to the website for more information.